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IMNG Medical News Group has provided physician specialists with authoritative coverage of medical meetings, breaking medical news and analysis, clinical trial results, updates on drug prescribing, pertinent summaries of clinical guidelines, and perspective and opinion from medicine thought leaders.
Updated: 18 min 5 sec ago

COPPS-2 curtails colchicine enthusiasm

Sat, 08/30/2014 - 6:00am
Patients undergoing cardiac surgery who took colchicine had significantly less postpericardiotomy syndrome than did those on placebo, but this protective effect did not extend to postoperative atrial fibrillation and pericardial or pleural effusions in the double-blind COPPS-2 trial.

Type B aortic dissections are all complicated and require TEVAR.

Fri, 08/29/2014 - 10:07am
Aortic dissection is a devastating condition afflicting an estimated two to eight per 100,000 people annually and comprises a large portion of the clinical entity known as the acute aortic syndromes. Patients presenting with an uncomplicated type B acute aortic dissection (TBAD) generally have low in-hospital mortality rates (2.4%-9%) when managed appropriately with anti-impulse therapy. However, survival continues to decrease with follow-up, with survival ranging between 80% and more than 95% at 1 year, progressing to approximately 75% at 3-4 years, and 48%-65% at 10 years. In late follow-up, the development of a new dissection with complications is estimated to occur in 20%-50% of patients. Complicated aortic dissections affect between 22% and 47%, and when present, mortality reaches more than 50% within the first week. TEVAR in these patients has been shown to be clearly indicated in a variety of studies with marked improvements in early mortality and late survival. Thus, one can see that aortic dissection is a disease that needs to be managed lifelong, and is associated with a high risk of mortality for the next 10 years after the initial presentation.

Bundled preventive care reduced surgical site infections

Wed, 08/27/2014 - 3:00pm
Implementing a systematic bundle of prevention strategies reduced the absolute rate of superficial surgical site infections after colorectal surgery by 14% at one institution.

VEGF-A value may stratify risk in pediatric heart transplant recipients

Wed, 08/27/2014 - 11:49am
SAN FRANCISCO (FRONTLINE MEDICAL NEWS) – Monitoring plasma vascular endothelial growth factor A (VEGF-A) may help identify pediatric heart transplant patients who are at increased risk for poor outcomes, according to a study reported at the 2014 World Transplant Congress.

Open surgery for 34% of inpatient breast biopsies

Wed, 08/27/2014 - 11:24am
Open breast biopsy accounted for 34% of breast biopsies in 25,965 U.S. inpatients between 2008 and 2010, a retrospective study found.

Study outlines risk factors for solid organ cancers after liver transplantation

Tue, 08/26/2014 - 2:11pm
SAN FRANCISCO (FRONTLINE MEDICAL NEWS) – The indication for liver transplant, the selection of immunosuppression therapy, and smoking status influence the long-term risk of new solid organ malignancies after liver transplantation, Dr. Sebastian Rademacher reported at the 2014 World Transplant Congress.

Early elimination of cyclosporine after heart transplant has renal benefit

Tue, 08/26/2014 - 12:09pm
SAN FRANCISCO (FRONTLINE MEDICAL NEWS) – Use of an everolimus-containing regimen with early stopping of cyclosporine after de novo heart transplantation improves renal function and reduces cardiac allograft vasculopathy, without compromising graft outcomes, new data suggest.

CPAP, adenotonsillectomy benefits similar for OSA in Down syndrome

Tue, 08/26/2014 - 10:09am
Adenotonsillectomy and CPAP achieve similar improvements in apnea-hypopnea index among children with obstructive sleep apnea and Down syndrome or mucopolysaccharidoses, although the benefits from continuous positive airway pressure are more immediate, researchers said.

Hold the central lymph node dissection for small parathyroid tumors?

Mon, 08/25/2014 - 3:58pm
BOSTON (FRONTLINE MEDICAL NEWS) – Central lymph node dissection may not be necessary in patients with small parathyroid carcinomas, results of a data review suggest.

Postbariatric cholecystectomy most common among Roux-en-Y patients

Wed, 08/20/2014 - 4:10pm
The overall rate of cholecystectomy after weight loss surgery is low, but it is more likely to occur among patients who experience excessive weight loss following their procedure and those who undergo laparoscopic Roux-en-Y gastric bypass.

HCV infection raises risk of death after kidney transplant

Wed, 08/20/2014 - 3:10pm
SAN FRANCISCO (FRONTLINE MEDICAL NEWS) – Infection with hepatitis C virus is a risk factor for poor outcomes after kidney transplantation, but infection with human immunodeficiency virus is not, finds a cohort study reported at the 2014 World Transplant Congress.