Current Projects

New research proposals requesting data from the STS National Database are assessed for overlap with active projects from all STS research programs, including PUF, A&P and Task Force on Funded Research (TFR). Please email the Research Center with any questions regarding this list.

Project Status Legend

  • Approved - Proposal has been approved for study by the A&P or PUF Task Force and its corresponding specialty review committee.
  • Analysis - Proposal is currently undergoing active analysis by the investigators and appropriate analytics center.
  • Abstract - An abstract for the proposal has been developed and submitted to a meeting.
  • Manuscript - A manuscript for the proposal has been drafted.

Updated August 28, 2020

Adult Cardiac Surgery Database (PUF)
Principal Investigator Proposal Title Project Status
Shinichi Fukuhara
University of Michigan
Non-aortic valve cardiac surgery in patients with transcatheter aortic bioprosthesis Approved
Jacob Raphael
University of Virginia    
Delineating thromboembolic complications after RBC transfusion in cardiac surgery patients Approved
Hari Mallidi
Brigham and Women’s Hospital
The effect of the 2018 UNOS donor heart allocation policy change on cardiac transplantation and durable LVAD implantation in women Approved
Marisa Cevasco
University of Pennsylvania
Disparities in mitral valve surgery Approved
Emily MacKay
University of
Transesophageal echocardiography in open cardiac valve and proximal aortic surgery: Practice patterns and impact on clinical outcomes Analysis
Tom Nguyen
University of Texas Health Science Center Houston
Trends and outcomes in adult cardiac surgery patients during the COVID pandemic Approved

Arminder Jassar
Massachusetts General Hospital

Correlation of hypothermic circulatory arrest duration and temperature with acute renal failure after aortic arch surgery Abstract
Thomas Bilfinger
Stony Brook University School of Medicine
Single versus multi-center surgeons' risk-adjusted mitral valve repair procedural outcomes (SURGEON MVR) Approved
Henry Tannous
Stony Brook University School of Medicine
Impact of coronary artery bypass graft clinical science research: The off-pump/on-pump treatment experience Approved
Gabor Bagameri
Mayo Clinic
Comparison of the neurological outcomes after aortic arch repair: Endovascular approach vs. the standard of care (Open Repair) Analysis
Frederick Lombard
Vanderbilt University Medical Center
Intraoperative processed EEG and delirium, neurologic complications and mortality after cardiac surgery Analysis
Neel Sodha
Rhode Island Hospital
Predicting hemorrhage and thrombosis in mechanical circulatory support: A study using machine learning Analysis
Shinichi Fukuhara
University of Michigan
Surgical explantation of transcatheter aortic valve: Results and clinical implications Manuscript
Oz Shapira
Hadassah Medical Center
Changing impact of repeat CABG on operative outcomes in the last two decades: Insights from the Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis
Anju Nohria
Brigham and Women's Hospital
Comparative outcomes of SAVR vs. TAVR in mediastinal radiation-associated aortic valve disease Manuscript
Bradley Taylor
University of Maryland
Impact of revascularization technique on the risk of stroke and mortality during coronary artery bypass grafting: The analysis of the STS Adult Cardiac Surgery Database Abstract
Victor Nauffal
Brigham and Women’s Hospital
Novel oral anticoagulants versus Warfarin for post-cardiac surgery atrial fibrillation Manuscript
Miklos Kertai
Vanderbilt University Medical Center
Intraoperative and postoperative dexmedetomidine and delirium, severity of postoperative pain and outcomes after cardiac surgery Manuscript
Mario Gaudino
New York Presbyterian Hospital
Trends in the use of multi-arterial coronary bypass grafting in young patients Manuscript
Jonathan Haft
University of Michigan
Pulmonary thromboendarterectomy (PTE) for chronic thromboembolic pulmonary hypertension (CTEPH) Abstract
Ankur Kalra
Cleveland Clinic Foundation
Direct oral anticoagulants and mechanical valves: Trends in utilization and outcomes  Abstract
Robert S. D. Higgins
Johns Hopkins University School of Medicine
Disparities in CABG outcomes – STS Database experience Manuscript
Hartzell Schaff
Mayo Clinic
Center volume and surgical outcomes in hypertrophic cardiomyopathy: What impacts outcomes? Analysis
Brent Keeling
Emory University School of Medicine
Trends in emergency coronary artery bypass surgery Manuscript
Tom Nguyen
University of Texas Health Science Center Houston, McGovern Medical School
Nationwide outcomes of less invasive mitral surgery versus conventional sternotomy: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database Manuscript
Daniel Engelman
University of Massachusetts – Baystate
Skeletonized versus pedicled bilateral internal thoracic arteries harvesting – effects on peri-operative outcomes: Analysis of the STS Adult Cardiac Surgery Database Manuscript
S. Chris Malaisrie
Northwestern University
30-day outcomes for sutureless rapid deployment valves compared to traditional bioprosthetic valves for aortic valve replacement Manuscript
Ravi Ghanta
Baylor College of Medicine
Outcomes of aortic valve surgery for chronic aortic regurgitation Abstract
Thomas Gleason
University of Pittsburgh Medical Center
Trends and outcomes of mitral valve surgery for papillary muscle rupture: An analysis of the Society of Thoracic Surgeons National Database Manuscript
Robert Hagberg
Hartford Hospital
Machine learning methods for mortality and morbidity after cardiac surgery Manuscript
Derek R. Brinster
Lenox Hill Hospital
Transfusion requirements in aortic root replacement  Manuscript
Michael J. Mack
The Heart Hospital Baylor Plano
Predicted risk of transfusion in isolated AVR Analysis
Toshinobu Kazui
The University of Arizona
Bilateral mammary artery use in high HbA1c patients Manuscript
Harlan M. Krumholz
Yale New-Haven Hospital
Using machine learning to update perioperative risk models with incorporating intraoperative data Manuscript
James R. Edgerton
The Heart Hospital Baylor Plano
Predicted risk of transfusion in isolated CABG Manuscript
Michael P. Macris
Memorial Hermann Health System
The impact of time interval between coronary angiography and cardiopulmonary bypass on acute kidney injury  Manuscript
Thomas Kelley
Dwight D. Eisenhower Army Medical Center
Effect of a balanced transfusion ratio on survival in patients in hemorrhagic shock after cardiac surgery  Manuscript
Donald Likosky
University of Michigan
Influence of Medicaid access on implantable durable left ventricular assist device usage and outcomes: A comparator study with heart transplantation  Analysis 
Dan Loberman
Brigham and Women’s Hospital
Myocardial preservation in minimal invasive mitral valve surgery Manuscript
Giovanni Filardo
The Heart Hospital Baylor Plano
Predicted risk of transfusion in isolated MVR and MV repair Analysis 
Joseph F. Sabik III
University Hospitals Cleveland Medical Center
Trends in use of FFR in patients undergoing surgical revascularization: Insights from the STS National Database  Abstract 
Thomas A. Schwann
Baystate Health
Elucidating surgeon and institutional volume – Outcome effects for multi-arterial and single-arterial coronary artery bypass grafting strategies  Analysis
Matthew Williams
University of Pennsylvania
Measuring the learning curve Manuscript
Andrei Churyla
Northwestern Memorial Hospital
SAVR +AFIB ablation and LAA closure versus TAVR in patients with pre-existing atrial fibrillation Manuscript
M. Scott Halbreiner
Allegheny General Hospital
Use of skeletonized versus pedicled internal thoracic artery: Is there a correlation with sternal wound infection  Manuscript
David L. Joyce
Medical College of Wisconsin
Minimally invasive versus conventional single vessel LIMA-LAD bypass grafting: A comparison of surgical outcomes from the STS National Database  Abstract 
Zain I. Khalpey
University of Arizona
Predictive strategies for the prevention of disease outcomes      Analysis
Arman Kilic
University of Pittsburgh Medical Center
Evaluating the predictive capabilities of machine learning algorithms in isolated aortic valve replacement Manuscript
Arnar Geirsson
Yale School of Medicine
Pattern and predictors of oral anticoagulant and antiplatelet use following aortic valve replacement and mitral valve surgery 


Adult Cardiac Surgery Database (A&P)
Principal Investigator Proposal Title Project Status
Gabriele Di Luozzo
Mount Sinai St. Luke’s Hospital
Nationwide trends and outcomes in the usage of adjuncts for spinal cord protection in patients undergoing open surgery for the descending thoracic or thoraco-abdominal aorta: 20-year analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database (FUTURE ANALYSIS) Approved
Robert S. D. Higgins
Johns Hopkins University School of Medicine
Utilization and outcomes of intra-operative transesophageal echocardiography during cardiac surgery: A national study from the Society of Thoracic Surgeons Adult Cardiac Surgery Database Abstract
Joseph Sabik
University Hospitals Cleveland Medical Center
Anticoagulation in postoperative atrial fibrillation: Effect of the CHA2DS2-VASc score on practice patterns and outcomes Abstract
Matthew Williams
University of Pennsylvania
Coronary artery bypass grafting with adjunct coronary endarterectomy: An analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database Abstract
Gorav Ailawadi
University of Virginia
Association between surgical volume and annular enlargement outcomes Abstract
Danny Chu
University of Pittsburgh School of Medicine
Optimal temperature for aortic hemiarch replacement Procedure with antegrade cerebral perfusion strategy: How warm is too warm? Analysis
Robert Hooker
INTEGRIS Baptist Medical Center
Prosthetic valve endocarditis In aortic valve surgery: The North American experience Abstract
Jennifer Lawton
Johns Hopkins Division of Cardiac Surgery
Gender disparities in surgical coronary revascularization Abstract
Thomas Schwann
University of Massachusetts - Baystate
The effects of peri-operative transfusions on intermediate term mortality in Medicare patients undergoing CABG – A report from the STS Cardiac Surgery Database 2011-2018 Analysis
Nicholas Teman
University of Virginia
Extracorporeal membrane oxygenation vs. right ventricular assist device for LVAD implant related right ventricular failure Abstract
Vinod Thourani
Medstar Heart and Vascular Institute
Outcomes in patients undergoing mitral valve operations for ischemic mitral regurgitation in the United States Analysis
Wilson Szeto
University of Pennsylvania 
Outcomes with elective open aortic valve replacement in patients with moderate or greater mitral regurgitation Manuscript
Thomas Bilfinger
Stony Brook University School of Medicine
Acute Type A aortic dissection (ATAAD) Repair in the US: An STS National Database Report (FUTURE ANALYSIS)


Khaled Abdelhady
University of Illinois at Chicago
Zachary Kon
University of Maryland School of Medicine
Jeffrey Milliken University of California Irvine School of Medicine
Less-invasive aortic valve replacement: Trends and outcomes from the Society of Thoracic Surgeons  Adult Cardiac Surgery Database  Manuscript
Prashanth Vallabhajosyula
University of Pennsylvania
Traditional total aortic arch replacement versus hybrid arch repair  Manuscript 
Chad Hughes
Duke University Medical Center
Contemporary results of aortic root operations in the United States Manuscript
Carmelo A. Milano
Duke University Medical Center
Does duration of left ventricular assist device support have an effect on orthotopic heart transplantation outcomes? Manuscript
George Tolis
Massachusetts General Hospital
TEVAR vs open repair of descending thoracic aortic pathology: Long-term outcomes Manuscript
Vinod Thourani
Medstar Heart and Vascular Institute
Relationship of volume and outcomes in those patients undergoing AVR ± CABG in the US Manuscript
Frank Sellke
Beth Israel Deaconess Medical Center
Evaluation of amiodarone use without anticoagulation for new postoperative atrial fibrillation (AF) after coronary artery bypass grafting (CABG) Manuscript
Arnar Geirsson
Yale University School of Medicine
The evolving burden of heart valve replacement for endocarditis due to drug abuse: clinical outcomes and predictors of reoperation (Approved as joint collaborative project with Dr. Juan Crestanello) Manuscript
Juan Crestanello
Mayo Clinic
The impact of recurrent intravenous drug associated endocarditis: how many re-operations we can perform? 
(Approved as joint collaborative project with Dr. Arnar Geirsson)


General Thoracic Surgery Database (PUF)
Principal Investigator Proposal Title Project Status
Jacob Klapper
Duke University Medical Center
Perioperative outcomes of thymectomy for patients with myasthenia gravis Abstract
Elisabeth Dexter
Massachusetts General Hospital
Is increasing operative duration associated with worse analysis outcomes for lung resection?
Christopher Seder
Rush University Medical Center
Impact of obesity on conversion to thoracotomy in video-assisted vs robotic-assisted pulmonary resections Abstract
Mark Allen
Mayo Clinic
A study of thoracic surgeon bias in lung cancer surgery Manuscript
Peter Kneuertz
The Ohio State University Wexner Medical Center
Trends and outcomes of pulmonary segmentectomy for non-small cell lung cancer by robotic, video-assisted thoracoscopic, and thoracotomy approach in the STS National Database Analysis
Henning Gaissert
Massachusetts General Hospital
Diagnostic accuracy in the STS-GTSD: Concordance of clinical and pathological staging in primary Non-Small Cell Lung Cancer Manuscript
K. Robert Shen
Mayo Clinic
Patterns of care and outcomes following lung volume reduction surgery in the United States Manuscript
Brandon H. Tieu
Oregon Health & Science University
Chylothorax after esophagectomy: A review of the STS National Database  Manuscript
Matthew A. Facktor
Geisinger Medical Center
ProvenCare® lung cancer collaborative Manuscript
Ikenna C. Okereke
University of Texas Medical Branch
Outcomes after surgical lung biopsy: An analysis of the STS National Database Approved
Christopher R. Morse
Massachusetts General Hospital
Role of increasing obesity in perioperative pathologic staging following resection of primary esophageal cancer  Manuscript
Douglas J. Mathisen
Massachusetts General Hospital
Predictors and impact of extended lymphadenectomy on outcomes following esophagectomy for primary esophageal cancer Manuscript
Nicholas Arndt
Rush University Medical Center
Redefining the risk of surgery for Stage IIIA (N2) non-small cell lung cancer: An analysis of the STS General Thoracic Surgery Database Manuscript
Daniel Boffa
Yale University School of Medicine
Impact of invasive nodal staging on nodal upstaging in surgically managed lung cancer  Manuscript
General Thoracic Surgery Database (A&P)
Principal Investigator Proposal Title Project Status
Daniel Miller and Elliot Servais
Wellstar Health System/Lahey Hospital and Medical Center
Quality assessment of reasons for open conversion during minimally invasive (thoracoscopic and robotic) lung 
resection and the associated morbidity and mortality
Phillip Linden
University Hospitals 
Cleveland Medical Center
Perioperative risk of each individual lobectomy Abstract
David Harpole
Duke University
Open versus minimally invasive repair of pectus excavatum Manuscript
Christopher Towe
University Hospitals Cleveland Medical Center
Classification of factors associated with successful early discharge after anatomic lung resection Manuscript
Nathaniel R .Evans
Thomas Jefferson University Hospital
Predictors of prolonged air leak and chest tube duration after lobectomy Manuscript
Yaron Perry
University Hospital Case Medical Center
Failure to rescue after esophagectomy: An analysis of postoperative complications and their effect on perioperative mortality Manuscript
Manu S. Sancheti
Emory University School of Medicine
Socioeconomic disparities impact outcomes of lung cancer resection, a review of the STS National Database Manuscript
Farhood Farjah
University of Maryland School of Medicine
Evaluating the impact of the volume pledge for lung cancer resections among General Thoracic Surgery Database participants Manuscript
Congenital Heart Surgery Database (PUF)
Principal Investigator Proposal Title Project Status
Jennifer Nelson
Nemours Children’s Hospital
Aortic valve replacement in young adults and adults with congenital heart disease:Clarifying the current and potential future roles for TAVR Manuscript
Viviane Nasr
Boston Children’s Hospital
The geographic distribution of pediatric cardiac anesthesiologists relative to cardiac surgeons and pediatric cardiac surgeries in the United States Analysis
Martina Steurer
Benioff Children's Hospital, UCSF
Associations between attained fetal growth and early postoperative outcomes in neonates with congenital heart disease Manuscript
Nicole D. Zantek
University of Minnesota
Risk factors for platelet transfusion and impact of platelet transfusions on outcomes in patients undergoing congenital heart surgery Analysis
Congenital Heart Surgery Database (A&P)
Principal Investigator Proposal Title Project Status
Marshall Jacobs
Johns Hopkins School of Medicine
Staged operative strategies in CHSD Abstract
David Bichell
Monroe Carrell Jr. Children’s Hospital at Vanderbilt
Surgical management of congenitally corrected transposition of the great arteries: Practice patterns and outcomes Analysis
Victor Morell
Children’s Hospital of Pittsburgh
Delineating the optimal operative approach for treating patients with transposition of the great arteries with ventricular septal defects and left ventricular outflow tract obstruction Abstract
Justin Long
Children’s Healthcare of  Atlanta/Emory University
Higher postoperative hematocrit and increased adverse outcomes in pediatric cardiac surgery patients Manuscript
James Tweddell 
Cincinnati Children’s Hospital Medical Center
Outcomes of airway disease patients undergoing congenital cardiac surgery Manuscript
Andrew Lodge
Duke University School of Medicine 
Factors associated with adverse outcomes in patients undergoing Fontan revision surgery Manuscript
Narutoshi Hibino
The Johns Hopkins Hospital
The prevalence, impact, and management of diaphragm paralysis following congenital cardiac surgery in children Manuscript
Faith Ross
Seattle Children’s Hospital
Associations between anthropometric indices and outcomes of congenital heart operations in infants and young children: An analysis of data from the STS National Database Manuscript
Jeffrey P. Jacobs
Johns Hopkins All Children’s Heart Institute
Creation and evaluation of a case mix index for pediatric and congenital cardiac surgery Analysis
Ram Kumar Subramanyan
Children’s Hospital, Los Angeles
Surgical outcomes following repair of tetralogy of Fallot with absent pulmonary valve syndrome Analysis
Robert D. B. Jaquiss
Duke University Medical Center
Post-operative cardiac catheterization in children undergoing congenital heart surgery: An analysis of the STS Congenital Heart Surgery Database Manuscript
Intermacs/Pedimacs Database (PUF)
Principal Investigator Proposal Title Project Status
Amin Yehya   
Sentara Heart Hospital
Characterization of outcomes in LVAD recipients with human immunodeficiency virus Approved
Renzo Loyaga-Rendon                Spectrum Health  Risk score development for stratification of survival in patients undergoing durable mechanical circulatory support: An STS Intermacs Database analysis Approved
Themistokles Chamogeorgakis
University of Michigan
Right ventricular support in the context of biventricular failure: An Intermacs analysis Approved
Jerry Estep
Cleveland Clinic
Predictors of hospital readmission burden and survival analysis in patients with contemporary continuous flow left ventricular assist device (CF-LVAD) Approved
Lucian Lozonschi  Medical University of South Carolina Ventricular arrhythmia post cf-left ventricular assist device placement – Trends within the STS Intermacs in the contemporary era Analysis
Meredith Brisco-Bacik
Temple University
Prevalence, predictors and prognostic importance of changes in renal function following continuous flow left ventricular assist device support: An Intermacs analysis
Sameed Khatana
Hospital of the University of Pennsylvania    
Trends in durable ventricular assist device implantation rates with the Affordable Care Act and Medicaid expansion and association of post-implantation outcomes with payor
Duc Thinh Pham        
Northwestern University
Risk assessment model for wait list mortality in left ventricular assist device patients Analysis
Edward Grandin        
Beth Israel Deaconess Medical Center
Assessing the impact of beta-blockers on late right heart failure and survival after left ventricular assist device implantation (PUF) Abstract
Karen Uzark            
University of Michigan
Quality of life in children on ventricular assist device (VAD) support: Analysis from Pedimacs Analysis

Please click here for additional information about current Intermacs projects in the A&P/PUF tracks.

Intermacs/Pedimacs Database (A&P)
Principal Investigator Proposal Title Project Status
Joanna Chikwe    
Cedars-Sinai Medical Center 
Contemporary outcomes of ventricular assist devices in the treatment of geriatric heart failure Abstract
Lynne Stevenson
Vanderbilt University Medical Center
Pre-implant Left Ventricular Assist Device strategies and subsequent short and long-term outcomes – A second look Approved
Francis Pagani
University of Michigan
Generalizability of MOMENTUM 3 clinical trial results to the “real world” Intermacs Experience Abstract
David Morales
Cincinnati Children's
Outcomes after ventricular assist device implantation in patients with Fontan palliation Analysis
James Bergin
University of Virginia
Defining a phenotype for failure in bridge to transplant LVAD therapy Abstract
Kenan Yount
University of Virginia
Effects of preoperative or postoperative dialysis on LVAD outcomes, patient survival, progression to transplantation and quality of life Abstract
Sung Min-Cho
Johns Hopkins
Real-world data of stroke in HeartMate 3, HeartMate II, and HeartWare and impact of center characteristics on stroke outcomes: An Intermacs analysis (Approved as joint collaborative proposal with John Kern) Abstract
John Kern
University of Virginia
Major adverse neurological event rate by centrifugal vs axial flow device in the modern era (Approved as joint collaborative project with Sung Min-Cho) Abstract
Shahnawaz Amdani Cleveland Clinic Model for end-stage liver disease excluding INR (MELD-XI) score predicts outcomes in pediatric patients supported with ventricular assist device: An analysis of the Pedimacs registry Abstract
Francisco Arabia
Banner Health/University of Arizona
Heart transplant outcomes post total artificial heart BTT Analysis
Jennifer Cowger
Henry Ford Hospital
Ventricular assist device patient phenotypes: What attributes describe long-term survival? Manuscript
Robert Niebler
Medical College of Wisconsin
Incidence and outcomes of, and risk factors for, neurological adverse events in children support with ventricular assist devices Manuscript
Josef Stehlik
University of Utah School of Medicine
Mortality by body mass index in adult heart transplant recipients – Direct to transplant vs. mechanical circulatory support bridge strategy Analysis
Bryan Whitson
The Ohio State University
Assessing the impact of surgical implant approach on perioperative right ventricular failure associated with left ventricular assist devices Manuscript

Please click here for additional information about current Intermacs projects in the A&P/PUF tracks.